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放射医学研究所

  • 姓 名:

    刘鉴峰

  • 单 位:

    天美麻花星空视频放射医学研究所

  • 教职岗位:

    准聘副教授

  • 聘任时间:

    2019-07-01

  • 一级学科:

    生物医学工程

  • 二级学科:

    生物医学工程

  • 联系方式:

    liujianfeng@irm-cams.ac.cn

  • 导师风采链接:

个人介绍

刘鉴峰,天美麻花星空视频研究员,北京协和医学院博士生导师,天美麻花星空视频创新药物放射性药代研究重点实验室主任,核医学应用研究室主任、辐射防护与药物研究室主任。天津市创新人才推进计划重点领域创新团队“纳米医用材料研发创新团队”负责人。获得国家优秀青年科学基金和天津市杰出青年科学基金资助,享受国务院特殊津贴入选天津市有突出贡献专家、天津市创新人才推进计划中青年科技创新领军人才等。


主要研究方向

研究方向为纳米医学、影像医学与核医学。主要从事多肽纳米自组装体系的制备及其医学应用领域科研工作,包括纳米药物载体、多模态分子影像探针及纳米放疗增敏剂研发等。


代表性成果

天美麻花星空视频

1. Cuihong Yang#, Ganen Mu, Ying Zhang, Yang Gao, Wenxue Zhang, Jinjian Liu, Wenwen Zhang, Paiyun Li, Lijun Yang, Zhimou Yang, Jie Gao*, Jianfeng Liu*. Supramolecular Nitric Oxide Depot for Hypoxic Tumor Vessel Normalization and Radiosensitization. Advanced Materials. 2022:e2202625. (IF=32.086)

2. Yuanhao Wu#, Yuan Yao, Jiamin Zhang, Han Gui, Jinjian Liu*, Jianfeng Liu*. Tumor-targeted injectable double-network hydrogel for prevention of breast cancer recurrence and wound Infection via synergistic photothermal and brachytherapy. Advanced Science. 2022:e2200681. (IF=17.521)

3. Xiaoxue Hou#, Yu-Xuan Chang, Yu-Xin Yue, Ze-Han Wang, Fei Ding, Zhi-Hao Li, Hua-Bin Li, Yicheng Xu, Xianglei Kong, Fan Huang,* Dong-Sheng Guo*, Jianfeng Liu*. Supramolecular radiosensitizer based on hypoxia-responsive macrocycle. Advanced Science. 2022:e2104349. (IF=17.521)

4. Yumin Zhang#, Zujian Feng#, Jinjian Liu, Hui Li, Qi Su, Jiamin Zhang, Pingsheng Huang, Weiwei Wang*, Jianfeng Liu*. Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance. Bioactive Materials. 2022:16, 359-371. (IF=16.874)

5. Yu Zhao#, Xiaoxue Hou, Jingshan Chai, Zhanzhan Zhang, Xue Xue, Fan Huang*, Jianfeng Liu*, Linqi Shi*, Yang Liu*. Stapled liposomes enhance cross-priming of radio-immunotherapy. Advanced Materials. 2022, 34(3): e2107161. (IF=32.086)

6. Haixue Jia#, Yuna Shang, Hongmei Cao, Yang Gao, Jinjian Liu, Lijun Yang, Cuihong Yang, Chunhua Ren, Zhongyan Wang* and Jianfeng Liu*. A minimalist supramolecular nanovaccine forcefully propels the Tfh cell and GC B cell responses. Chemical Engineering Journal. 2022, 435: 134782. (IF=16.744)

7. Qian Wang#, Meng Xiao#, Dianyu Wang, Xiaoxue Hou, Jie Gao, Jinjian Liu and Jianfeng Liu*. In situ supramolecular self-assembly of Pt(IV) prodrug to conquer cisplatin resistance. Advanced Functional Materials. 2021, 31(27): e2101826. (IF:18.808)

8. Shuang Tian#, Linzhu Su, Yong Liu, Jingjing Cao, Guang Yang, Yijin Ren, Fan Huang, Jianfeng Liu*, Yingli An, Henny C. van der Mei*, Henk J. Busscher* and Linqi Shi*. Self-targeting, zwitterionic micellar dispersants enhance antibiotic killing of infectious biofilms-an intravital imaging study in mice. Science Advances. 2020, 6(33): eabb1112. (IF:14.957)

9. Yanbin Cai#, Haosheng Shen, Jie Zhan, Mingliang Lin, Liuhan Dai, Chunhua Ren, Yang Shi, Jianfeng Liu*, Jie Gao*, Zhimou Yang*. Supramolecular “Trojan Horse” for nuclear delivery of dual anticancer drugs. Journal of the American Chemical Society. 2017, 139(8): 2876-2879. (IF: 15.419, C100, ESI)

10. Cuihong Yang#, Chunhua Ren, Jie Zhou, Jinjian Liu, Yumin Zhang, Fan Huang, Dan Ding, Bing Xu*, Jianfeng Liu*. Dual fluorescent- and isotopic-labelled self-assembling vancomycin for in vivo imaging of bacterial infections. Angewandte Chemie-International Edition. 2017, 56(9): 2356-2360. (IF: 16.823)